Keegan Pietersen scored a brilliant 82 as South Africa won the third Test by seven wickets and chased down their challenging target of 212 to win the series 2-1 over India on a Newlands pitch.
It is only the fourth time in 133 years that a team has scored more than 200 runs in Cape Town, and after Dean Elgar's team won the second Test by seven wickets when they needed 240 in the fourth innings.
Pietersen, who was the leading scorer in the series with 276 runs and won both player of the match and player of the series awards, was the anchor for the home side on a tough wicket to bat on Friday.
Still, there were significant unbeaten contributions from Rassi van der Dussen (41) and Temba Bavuma (32), who put on an unbroken 57-run stand for the fourth wicket.
The result means that world No. 1 ranked team India is still on the hunt for a maiden Test series win in South Africa, which had high hopes when it won the opening match.
The teams will now play three One Day Internationals (ODIs) starting in Paarl from Wednesday.
Captain Elgar described the win as a significant step for his side, who have lost several veteran players to retirement in recent years.
"I'm so excited. I can't be too proud of a group of players," he said. "We were thrown under the sword quite a few times in this series and people responded wonderfully."
South Africa started the day 2-101 and there were a lot of alarms against high quality Indian fast bowlers who could have had more reward with better luck.
The visitors only had themselves to blame, however when Cheteshwar Pujara dropped Pietersen for 59 at first slip, the delivery from Jasprit Bumrah had a regular chance.
South Africa ran out of luck and Pietersen looked in control before Shardul Thakur cut the ball past his stumps 40 minutes before lunch. He played a brilliant innings of 72 runs in just 113 balls in the first innings.
Elgar heaped praise on Pietersen, saying, "He is a dominant force in domestic cricket, it was great to see him in a great series."
"How long does he grow to be, there is still a lot to improve. The world is his oyster."
India, however, had become extremely frustrated with the technique used for dismissal referrals and could land themselves in some trouble with their deliberate on-field remarks at the stump microphone.
His disappointment boiled over when he thought Van der Dussen had caught him off Mohammed Shami's delivery, although the bowler himself showed no interest and returned to his mark.
But captain Virat Kohli sent the not out decision for review, and though there was a spike on ultra-edge technique, it was ruled that the batsman had hit the ground.
This followed India's fury on Thursday when they believed they had home captain Dean Elgar leg-out before the wicket, but after being given out, ball-tracker technology suggested the delivery bounced on the stumps. Was being
Yet Kohli was complacent in defeat. “It was a very tough series, but South Africa did surprisingly well to come back in the second Test and then capitalize on the same momentum in the third.
"I think in both the Tests he won, he was a lot more clinical with the ball in moments of crisis, and to be honest, there was even a slight lack of concentration on our part, which cost us.
"They deserved winners in the end."